Volumen 15 número 3 - Octubre 2018
ISSN 0718-0918
Tabla de Contenidos > Caso Clínico
SÍNDROME DE SENSIBILIDAD A DROGAS CON EOSINOFILIA Y SÍNTOMAS SISTÉMICOS (DRESS) ATÍPICO POR CARBAMAZEPINA, A PROPÓSITO DE UN CASO PEDIÁTRICO
Rojas Torres Paula Fernanda1, Stevens Cortés Paula Rosario2, Geraldo Von Bennewitz Alfredo Eduardo1, Araya Navarrete José Roberto1
1 Interno de Medicina. Universidad San Sebastián, sede Concepción, Chile
2 Médico Pediatra. Servicio de Pediatría, Centro Asistencial Dr. Víctor Ríos Ruiz

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Background: The drug sensitivity syndrome with eosinophilia and systemic symptoms (DRESS) is usually accompanied by eosinophilia. It is a disease that endangers the life of the patient. It occurs as an adverse reaction to infections and medications, usually associated with the use of antiepileptics.

Case report: A 6-year-old patient, male, with a recent diagnosis of epilepsy, who consulted the Emergency Department two weeks after initiating treatment with Carbamazepine because of a condition characterized by facial predominance erythema, exacerbated by sun exposition. Subsequently presented fever with episodes up to 40 ° C, which was associated with seizures. After an exhaustive study, atypical DRESS syndrome (without eosinophilia) was made, initiating corticoid treatment with favorable clinical response.

Discussion: DRESS syndrome is a disease difficult to diagnose because of its multiple differential diagnoses and lack of diagnostic criteria. Immediate suspension of the causative drug is essential to prevent progression of the disease and initiate early treatment

Keywords: Drug Hypersensitivity Syndrome, Carbamazepine, Corticoid.
Revista Pediatría Electrónica
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Correo electrónico: gmedina.uchile@gmail.com
ISSN 0718-0918